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15% increase in GFR and RPF compared to healthy subjects, which is reversible in most but not all patients by surgical removal of pituitary adenomas [62, 72, 96]

Researcher Loren Pickart, PhD, who first isolated GHK from human plasma, described it as having a "profound effect on the reset of human genes toward a more youthful state." More recent genomic analyses confirm that GHK-Cu shifts gene expression patterns in aging tissue toward patterns characteristic of much younger tissue effectively acting as a biological reset at the cellular level