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At the 12th week, the mice demonstrate significant hepatic steatosis, with blood alcohol concentrations (BACs) reaching 100150 mg/dL, accompanied by mild liver injury, albeit without apparent liver fibrosis (Zhu et al., 2022)

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Plin1 expression was largely undetectable in samples from mice under 48 weeks of age, while detectable levels were observed in both male and female mice aged 5871 weeks (Supplementary Tables T1 and T2, and Supplementary Figure S3)

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