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3 Antifungal resistance mechanisms The only antifungal medications now available for treating invasive fungal infections are polyenes, azoles, and echinocandins, notwithstanding the concerning effects of these infectious agents on human health (Table 1 and Figure 2) (Lee et al., 2021)

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Our results are clinically relevant and consistent with clinical reports that the secretory capacity of -cell was diminished in first-degree relatives of individuals with T2DM even before the onset of obesity and insulin resistance 32