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Physicochemical Profile Appearance: White to off-white lyophilized powders Solubility: Soluble in sterile water and aqueous buffers Stability: Stable under dry, refrigerated conditions

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Potential participants without a diagnosis of diabetes and with an MMSE score of 24 or greater will be asked to give full informed consent and to provide a blood sample and, if eligible, have their results and contact information passed to the OPEN study team