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A promising therapeutic target is BDNF, which is essential for neuronal survival, plasticity, and development, particularly in RGCs

Biotin deficiency is rare but can occur in specific groups: High-Risk Groups: People with metabolic disorders or malnutrition Alcoholics and athletes Epilepsy patients , elderly , and those with gastrointestinal surgery Pregnant women (studies show 50% develop deficiency due to increased vitamin demand) Diabetes patients Dietary Causes: Long-term consumption of raw egg whites contains avidin , a protein that binds biotin and prevents absorption

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What is the reason why the secretion of an orexigenic hormone, such as ghrelin, and also that of an anabolic hormone, such as GH, is lost with aging