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orcid.org/0000-0002-1107-3024 This article was submitted to Pharmacogenetics and Pharmacogenomics, a section of the journal Frontiers in Genetics Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

2020;29:104914 Conflicts of interest: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

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10.3389/fcell.2021.765859 124 TarangeloA.MagtanongL.Bieging-RolettK

A common protocol, for example, is to begin with about 20 mg of NAD+ administered subcutaneously and gradually increase the dose over subsequent injections up to around 100 mg per injection