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Venlafaxine ER blocks the norepinephrine transporter in the brain of patients with major depressive disorder: a PET study using [18F]FMeNER-D2

doi: 10.1371/journal.pone.0004710 10 AntalisCJArnoldTRasoolTLeeBBuhmanKKSiddiquiRA

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Among the most widely used mechanisms are reduction-sensitive disulfide (-SS-) and diselenide (-SeSe-) linkages, which can be cleaved by intracellular GSH to activate drug release or imaging functions [16]