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The mechanism of VM formation has not been fully elucidated, and the potential mechanisms reported in current literature include EMT, hypoxia, cancer stem cells, vascular endothelial-cadherin, MMP, and so on (89, 92)

The cumulus-oocyte complexes (COCs) with at least three complete and dense layers of cumulus cells and uniform granular cytoplasm were selected for in vitro maturation under a stereo microscope

EGR1 regulates angiogenic and osteoclastogenic factors in prostate cancer and promotes metastasis