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(D) Unstable atherosclerotic plaques are prone to rupture and can cause sudden thrombotic occlusion of the artery, blocking blood flow and resulting in fatal clinical complications, including myocardial infarction, stroke, pulmonary embolism and peripheral artery disease

While circRNAs employ diverse molecular mechanisms and functions, current research on their roles in ARCs has largely focused on their function as miRNA sponges and their interactions with proteins (171,174,184-186), suggesting that novel functions or mechanisms remain to be identified

Results from the EPIC study

Storage Publications (5) Journal Impact Factor Most Recent Nat Commun CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signalling

PMID 16746382