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Karkkainen J, Laitinen T, Markowicz-Piasecka M, Montaser A, Lehtonen M, Rautio J, Gynther M, Poso A, Huttunen KM

The skin is cleaned with an antiseptic wipe at the injection site, usually the upper outer arm, and the intramuscular injection is given with a fine needle in around ten seconds

The precursor quantification strategy was set to robust LC (high accuracy) with retention-time-dependent cross-run normalization

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As neurons contribute to only up to 10% of brain volume, heterology in neuronal population and non-phagocytic nature of neurons are the common challenges imposed in targetability