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Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression

Together, these findings demonstrate that, in contrast with acute exposure, chronic disruption of iron homeostasis with consequent GSH depletion remodels cellular redox homeostasis over time, inducing a state we term chronoferroptosis: a persistent ferroptotic adaptation characterized by coordinated alterations in iron-handling and antioxidant defense proteins that may represent early vulnerability to neurodegenerative pathology

Balendiran, Rajesh Dabur et Deborah Fraser, The role of glutathione in cancer , Cell Biochemistry and Function , vol

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Think of glutathione as your internal guardian, protecting your cells from harm and ensuring your body operates at its best