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Flynn McGuire, a chief medical resident at the University of Utah Health, US, said there are valid concerns about the current state of the evidence base

Corticosteroid-impairment of healing and gastric pentadecapeptide BPC-157 creams in burned mice

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Aged-monkey studies reported changes in evening melatonin and cortisol rhythms

Reports have described possible increases in circulating growth hormone and IGF-1 over time, alongside observations of tissue-level changes such as dermal thickness and cellular proliferation