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The function of ERK1/2 leads to an increase in cellular mitogenic messages, which is indirectly triggered by PKA through the increased intracellular calcium induced by PLC/PKC events, both of which, according to the description, have been stimulated by IGF activity [53, 65]

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According to the last investigation is presumed that gastric juice should contain one other high-molecular compound with protein structure having organo-protective activity which could contribute to the stomach integrity and be also of benefit for many other organs after its distribution through organism