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Neuritin attenuates cognitive function impairments in tg2576 mouse model of Alzheimer's disease

The samples collected for biochemical assays included plasma for Nf-L measures, whole brain tissue and plasma for PK analysis of unbound inhibitor exposure levels, and frontotemporal cortex brain and spinal cord tissues for immunoblotting soluble and insoluble protein fractions (Fig

Contacts that provided robust cortical control signals for closed-loop aDBS, which improved clinical efficacy while minimizing adverse effects, were more proximal to SCAN than to effector regions (Extended Data Fig