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Mild GI symptoms are common with weight loss drugs but typically ease as your body gets used to the medication

In cautious research discussion, no the emphasis is on titrating each compound independently and slowly, never pushing both to maximum simultaneously, because the combination has never been tested for safety in humans

Lyons GH, Judson GJ, Ortiz-Monasterio I et al (2005) Selenium in Australia: selenium status and biofortification of wheat for better health

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This method bypasses the digestive system, allowing for maximum absorption and faster results compared to oral supplements