interaction of chloroacetamide electrophiles with cellular glutathion NCBP1 stress signaling drives alternative S6K1 splicing inhibiting translation Selective covalent targeting of GPX4
Selective covalent targeting of GPX4 using masked nitrile oxide electrophiles Nature Chemical Biology Glutathione Transferases: Potential Targets to Overcome Chemoresistance in Solid Tumors Glutathione Dynamics in Subcellular Compartments and Implications for Drug Development PMC Electrophilic compound screening identifies GPX4 dependent ferroptosis as a senescence vulnerability Nature Cell Biology Discovery of novel benzylaniline derivatives containing chloroacetamide as GPX4 inhibitors with potential efficacy in triple negative breast cancer ScienceDirect
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