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Stage II (mild) 6-15

} Anti-Inflammatory Treatment The use of steroids such as hydrocortisone in ME has been prompted by two considerations, firstly the observation that plasma cortisol concentrations tend to be low in ME, in contrast to what is found in depression, and secondly the fact that cytokines have been implicated in the causation of ME and may stimulate inflammation, suggesting that anti-inflammatory drugs such as steroids may have a role in treatment

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