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Based on clinical research involving AD and MCI patients, it is now indicated that GSH depletion occurs prior to amyloid A plaque formation and tau phosphorylation in AD [31]

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IKKbeta is essential for protecting T cells from TNFalpha-induced apoptosis Immunity 2001 14 : 217230 Senftleben U, Cao Y, Xiao G, Greten FR, Krahn G, Bonizzi G, Chen Y, Hu Y, Fong A, Sun SC, Karin M