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5-amino-1-methylquinolinium injection also upregulates GLUT4 (glucose transporter 4) expression, promoting glucose transport into adipose and muscle cells and reducing blood glucose accumulation

Sawangjit R, Thongphui S, Chaichompu W, Phumart P

In the SURMOUNT-1 trial, people treated with tirzepatide lost up to 22.5% of their body weight over 72 weeks , making it even more effective than semaglutide (NEJM tirzepatide study)