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Some studies suggest interaction with inflammatory signaling markers in experimental models, though conclusions remain preliminary

[DOI] [PMC free article] [PubMed] [Google Scholar] 107.Heier C, Xie H, Zimmermann R

Regarding the quantitative results of meat samples determined by the conversion SIDA method, lower total B12 levels were obtained compared to the corresponding values from the previous study using the native SIDA method (Electronic Supplementary Material Table S3)

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These findings suggest that while corticosteroids may offer quicker short-term pain relief, prolotherapy appears to provide more sustained analgesic effects in the long term, as reflected by more favorable VAS scores