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Additionally, the deposition of laminin, a key component of the basement membrane crucial for vascular integrity, further underscored the vascular perturbations characteristic of EAE (Roscoe and Welsh 2009)

MOTS-c has been shown to prevent muscle atrophy by reducing myostatin levels, a negative regulator of muscle mass

The release of vasoactive intestinal peptide (VIP) and acetylcholine (Ach) by submucosal neurons stimulates the enterocyte and Cl enters by co-transport with sodium and potassium through the basolateral Na + -K + -2Cl channel

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Consistent with the in vitro results, the phosphorylation levels of Akt and GSK3 and the expressions of -Catenin and Wnt10b in the dorsal skin of mice were significantly increased after WECP treatments in a dose-dependent manner