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Expanding our analysis to additional cancer types, we found that Lars2 was not only overexpressed in breast cancer, but also significantly upregulated in most other tumor types examined (Extended Data Fig

Kesterson et al., 2016)

Consequences of Glutathione Deficiency Low glutathione levels can lead to: Increased oxidative stress and cellular damage: Without adequate glutathione, free radicals accumulate and damage DNA, proteins, and lipids