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7 INTS12 phosphorylation and the Integrators endonuclease activity are required for establishing UV-induced Pol II elongation wave

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It is a signal to slow down and evaluate the delivery method, not necessarily a sign of toxicity

Consequently, the balance between system Xc and glutamate transport is disrupted, leading to both a reduced intracellular uptake of glutamate and an inhibition of GSH synthesis due to the lack of necessary raw materials (87)

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