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Furthermore, in mice the highest concentrations of GSH are in the cortex followed by the cerebellum, hippocampus and striatum (108) suggesting differential sensitivity of different brain regions to damage from oxidative stress

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Structure 23:14261436 Rodamilans B, Muoz IG, Bragado-Nilsson E, Sarrias MR, Padilla O, Blanco FJ, Lozano F, Montoya G (2007) Crystal structure of the third extracellular domain of CD5 reveals the fold of a group B scavenger cysteine-rich receptor domain

NAC in a weight-based dosage for younger children and age-appropriate dose for older patients (6001,200 mg per day) is recommended to be given to patients of CF