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General principles and experimental design Choose methods that (1) resolve the chemical species of interest (discriminating O 2 from H 2 O 2 and from OH-derived footprints rather than treating ROS as a single entity), (2) report from the correct compartment (matrix vs

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doi: 10.1016/j.molcel.2019.09.007 16 LinRElfSShanCKangHBJiQZhouLet al