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For a substance or method to be added to the List, it must be determined that it meets at least two of the following three criteria: It has the potential to enhance or enhances sport performance It represents an actual or potential health risk to athletes It violates the spirit of sport The full 2024 List was published on 28 September 2023, giving more than three months notice to athletes, their entourage, and other stakeholders, enabling them to acquaint themselves with any modifications

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[12] The lethal dose for humans is considered theoretically between 3 and 5 ml per kg

The authors reported modestly higher objective sleep efficiency and shorter sleep latency in the DSIP arm versus placebo, but subjective sleep-quality measures did not improve and the authors themselves concluded that short-term treatment of chronic insomnia with DSIP is not likely to be of major therapeutic benefit. That is the strongest controlled human sleep study in the literature, and its conclusion is negative to modest

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