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A complete blood count (CBC) can also reveal megaloblastic anemia, a hallmark of B12 deficiency

On the other hand, the use of animal models to study invasive meningococcal disease, in addition to presenting the obvious difficulties in investigating aspects of the extracellular/intracellular phase of meningococcal infection, is hampered by the fact that meningococcus has a very narrow host specificity, essentially restricted to humans

Fibroblasts were cultured in DMEM/F12 (Life Technologies) supplemented with 20% FBS (Pan Biotech) and penicillin/streptomycin

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