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2, compounds offormula1, e.g., wherein R=CH 3 , function as prodrug forms of L-cysteine (2), liberating this sulfhydryl amino aciuc by nonenzymatic ring opening and hydrolysis

Caspase-1 expression resulted in WT IL-1 cleavage into its active p17 fragment, which was detected in both cell lysates and supernatants and, as expected, its processing was blocked by treatment with the pan-caspase inhibitor ZVAD-fmk (Fig

[9] IIH is treated mainly through the reduction of CSF pressure and IIH may resolve after initial treatment, may go into spontaneous remission (although it can still relapse at a later stage), or may continue chronically

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