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Meanwhile, the control group displayed a significant rise in STAT3 levels, a change not observed in the L-carnitine group

4.2 Influence on tumor microenvironment and immune evasion 4.2.1 Interactions with immune system Different cell populations, such as endothelial cells, tumor invading immune cells [e.g., myeloid-derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs)], immunosuppressive cytokines of the extracellular matrix, and abnormal blood vessel systems make up the tumor microenvironment (TME) (143)

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[DOI] [PubMed] [Google Scholar] Pierre F, et al

Increased lipopolysaccharides (LPS) theory In a healthy gut environment, bacterial translocation across the intestinal barrier is typically prevented [39]