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The NEJM article discusses people who had strong reactions to dose 1 and what they did to counter them

doi: 10.1016/bs.apha.2022.07.003

Safety profile comparable to GLP-1 agonists when properly titrated [12]

In recent years, rapid advancements in ferroptosis research have led to the discovery of many effective ferroptosis regulators for clinical applications, and these discoveries have opened new avenues for treating ferroptosis-related diseases, with some showing promising clinical prospects