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Eur Urol 82(4):365-373, 2022

152 Maca Maca ( Lepidium meyenii ) is a South American plant in the Brassica family used historically to treat infertility and other womens hormonal health problems

The datasets were all generated from the ROSMAP cohort, these included the single cell transcriptomic data from the prefrontal cortex region (snRNAseqPFC_BA10) (Syn18485175) 52 ( bulk RNA-seq data of dorsolateral prefrontal cortex (DLPFC), posterior cingulate gyrus (PCG), and anterior cingulate (AC) regions (syn3388564) 134 ( and the non-targeted metabolomics data form DLPFC region (syn3157322) ( Key clinical and pathological features of de-identified subjects included in these studies can be found in Supplementary Data 1

Mediator contributes to the formation of condensin-mediated genomic contacts and chromatin domains To investigate the involvement of mediator in shaping 3D chromosome architecture during mitosis, we performed in situ Hi-C using mitotic cells in which Pmc4 proteins were degraded through the AID system (Fig