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By William Misner Ph.D

LC-MS/MS LC separation was done on a Dionex Nano Ultimate 3000 (Thermo Scientific) with a Thermo Easy-Spray source 17

NRF2 coordinates with several antioxidant pathways in response to oxidative stress (Figure 2)

Furthermore, both obesity and diabetes are accompanied by significant increases in ROS and decreases in NRF2 and GPX4 levels, indicating a weakening of antioxidant capacity and activation of the ferroptosis process