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10.1523/JNEUROSCI.0482-13.2013 45 ForetM

CJC-1295 with DAC carries a drug-affinity-complex modification that binds serum albumin, extending the half-life to approximately six to eight days

In human studies, Nrf2 suppression has been linked to cataract formation in lenses collected from diabetic and older patients, with the upregulation of Keap1 (an Nrf2 suppressor) found in these individuals