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Maternal hypothyroidism caused by iodine deficiency is associated with adverse pregnancy outcomes and impaired fetal growth, such as spontaneous abortion, premature birth, fetal death, low birth weight, neonatal mortality, growth restriction, altered cognitive development (cretinism, language disorders, altered motor development) [119]

Vitamin B12 helps regulate homocysteine levels in the blood, an amino acid linked to an increased risk of heart disease when elevated

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Therefore, expectations should be realistic

However, its role in injury-induced vascular remodelling remains unclear