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Since levels of tryptophan and its intestinal metabolites, tryptamine and indoleacetic acid, remained unchanged (data not shown), as to the reduction in indoxyl sulfate, several mechanisms might be speculated, i.e., suppressed indole production in intestinal cells, decreased indoxyl sulfate generation in the body, or increased clearance by E-HD as suggested elsewhere 50

Class III peroxidases are a large group of enzymes that are unique to plants 15

Furthermore, human Grx1 reacts twenty times faster with GSH than with L-cysteinylglycine or L-cysteine, revealing that the preference for GSH also depends on its -glutamyl moiety 19

tefani M, Toki S (2020) Serum 25-hydoxyvitamin D concentrations in relation to Hashimotos thyroiditis: a systematic review, meta-analysis and meta-regression of observational studies

Nicotine, cotinine and 3-hydroxy-cotinine (OH-cotinine) were measured in PBS using a quantitative liquid chromatography coupled to tandem mass spectrometry (LCMS/MS) method, based on a previously validated method for saliva (as established in 39 )