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Establishment of a humanized animal model of systemic sclerosis in which T helper-17 cells from patients with systemic sclerosis infiltrate and cause fibrosis in the lungs and skin

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Early diagnosis and treatment can prevent serious complications and, in most cases, symptoms are reversible with appropriate supplementation

Also improves mood and quality of sleep, increases metabolism and helps reduce stress

In this fashion, we hope to provide data that will support our conclusion that the intestinal paracellular space is a major route of transport of water and small solutes such as ions and small soluble organic molecules between the lumen and submucosal space, and not a means by which large molecules, lipophilic substances, or macromolecular structures such as proteins, particulate matter, or intact bacteria are absorbed