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This substantiates the evidence that the spared white matter holds the key to the functional motor recovery of the hind limbs after SCI and is closely correlated with the functional restoration of the paralyzed hind limbs [50,51,52]

In certain circumstancessuch as pregnancy, concurrent illness, or rapid metabolic turnoverB12 requirements may increase, and dosing adjustments may be necessary under medical supervision

In: Lewin GR, Carter BD (eds) Neurotrophic factors

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doi: 10.1371/journal.pone.0024930