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[23] Low folate status with the consequent loss of FAD enhances the thermolability of the enzyme, thus providing an explanation for the normalised homocysteine and DNA methylation levels in folate-replete 677TT individuals

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Activating Nrf2 can also start autophagy, a cellular process that helps the bodys natural defense by getting rid of bacteria inside cells and damaged organelles

Treatment involves discontinuing the suspected drug, administering the detoxifying agent N-acetylcysteine (NAC), and providing prompt systemic supportive care

Reactive oxygen species (ROS) have also been linked to bone health, inhibiting osteoblast differentiation and increasing osteoclastogenesis, leading to bone resorption (Wauquier et al., 2009