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The angiogenic effect of copper has been well-recognized, which is presumed to attribute to the regulation of factors involved in vessel formation and maturation, especially the pro-angiogenic factor, namely vascular endothelial growth factor (VEGF), and its major transcription factor, namely hypoxia-inducible factor-1-alpha (HIF1) [36]

Since the effect of cold laser therapy on unborn children is unknown, its suggested that pregnant women avoid this type of treatment

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doi: 10.1021/acs.chemrestox.9b00152 Summary Keywords oxidative stress, glutaredoxin, thioredoxin, E

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