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Johnny's main symptoms were pains in the muscles and joints with some red blotches on the skin

Thyroid function testsTSH, free T4, total T4, and T3assess metabolic status

doi: 10.1002/tox.22405 63 ForoozanfardFSadatZ

HPF1 interacts with several critical residues (Trp1014, Ser1012, Leu985, His826, and Leu1013) in the catalytic domain of PARP1 through its Lys307, Asp283, Cys285, Phe268, and Phe280 residues in the C-terminal domain