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TSC1-KO and 4E-BP1/2-DKO MEFs were previously described 43,44

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Longer cycles of 6+ weeks have not been studied in humans and may lead to diminished returns[1]

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Specifically, the ability of vitamin C to scavenge free radicals can reduce the degree of oxidative stress and increase the viability of nerve cells in the cerebral cortex and striatum (Ballaz and Rebec, 2019)