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Prolonged administration of high-dose ALA has been shown to reduce the catalytic activity of essential biotin-dependent enzymes in the liver, such as pyruvate carboxylase, by up to 35%

The presence of L-Carnitine and Co-Enzyme Q10 supports natural cellular energy production, which may help maintain energy and reduce tiredness

Model building The maximal effect (E max ) model built up via non-linear mixed-effect modeling (NONMEM, edition 7, ICON Development Solutions, Ellicott City, MD, United States) was used for analysis

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Anche l'agnello e il maiale sono buone fonti, fornendo all'organismo una quantit sufficiente a soddisfare il suo fabbisogno