Disclosures: Jessica Frankeberger: Nothing to Disclose, Melissa Choz: Nothing to Disclose, Tatyana Kushner: Gilead: Grant/Research Support, Gilead: Advisor, GSK: Advisor, Eiger: Advisor, Nancy Reau: Gilead: Grant/Research Support, eiger: Grant/Research Support, abbott: Consultant, Arbutus: Consultant, Gilead: Consultant, VIR: Consultant, Salix: Consultant, Salix: Grant/Research Support, AbbVie: Grant/Research Support, Adriane Wynn: Nothing to Disclose, Natasha Martin: Nothing to Disclose 1744 ESTIMATING LOCAL TRANSMISSION DYNAMICS OF HEPATITIS A VIRUS INCREASED INCIDENCE AMONG MEN WHO HAVE SEX WITH MEN IN NEW YORK CITY AND CALIFORNIA, 2016-2019 Oluwatosin Jegede 1 Ravi Goyal 1 Christl Donnelly 2 Megan Hofmeister 3 Lauren Stockman 4 Olivia Arizmendi 4 HaeNa Waechter 5 Julia Latash 5 Natasha Martin 1 , 1 University of California San Diego, 2 University of Oxford, UK, 3 Centers for Disease Control and Prevention, USA, 4 California Department of Public Health, 5 New York City Department of Health and Mental Hygiene Background: Hepatitis A is a vaccine-preventable disease

does the latter relapse refer to non-drug relapse? Response: We have replaced this sentence with: Enhanced D1 receptor signaling would also explain why addicts are more prone to relapse when stressed or hungry, both conditions that augment ghrelin secretion and sensitivity. There are many abbreviations used in the text that are not found in the abbreviation list (given abbreviations are not always defined upon first use, it is critical that they be defined somewhere). Response: All abbreviations have been added to the abbreviations list, and each abbreviation is now written out in full when first used
Jude EB, Blakytny R, Bulmer J, Boulton AJ, Ferguson MW (2002) Transforming growth factor-beta 1, 2, 3 and receptor type I and II in diabetic foot ulcers
Chem Phys Lett 521:9197 Prathna TC, Chandrasekaran N, Mukherjee A (2011) Studies on aggregation behaviour of silver nanoparticles in aqueous matrices: effect of surface functionalization and matrix composition
Collagen production naturally diminishes with age, contributing to the appearance of fine lines and wrinkles, and sagging skin