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This familiarization effect is also reflected in their blood corticosterone levels, which decrease once the mice become more accustomed to the arena before behavioral testing [206]

(74) found that NOR had a pro-apoptotic effect on FLSs of AIA rats, and its molecular mechanism was achieved by promoting the release of cytochrome C, regulating the Bax/Bcl-2 expression-mediated mitochondrial dependent pathway, and up-regulating the p53 pathway

Moreover, our results show an inverse relationship between angiogenesis and the level of loading, as more blood vessels were detected in tendons subjected to less loading