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This familiarization effect is also reflected in their blood corticosterone levels, which decrease once the mice become more accustomed to the arena before behavioral testing [206]

(74) found that NOR had a pro-apoptotic effect on FLSs of AIA rats, and its molecular mechanism was achieved by promoting the release of cytochrome C, regulating the Bax/Bcl-2 expression-mediated mitochondrial dependent pathway, and up-regulating the p53 pathway

Moreover, our results show an inverse relationship between angiogenesis and the level of loading, as more blood vessels were detected in tendons subjected to less loading

doi: 10.1186/s12967-019-1885-4 109 HunterC