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Presented at the 25th World Congress of Dermatology 2023, Singapore 4

MacRae et al, 2007)

Nguyen et al., 2003)

Unlike the trxB strain, where nearly all the AP activity is in the cytoplasm, the low level of activity in a wildtype strain is due to the small amount of AP that gets exported to the periplasm despite the lack of a signal sequence (Derman et al ., 1993a,b)