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In vivo, the ITT results did not differ between N5-WT and N5-Tr or C57BL/6N mice

followed eight patients with congenital lactic acidosis who received oral DCA (5.12 mg/kg every 9 h) for a duration ranging from 5.1 to 7.16 years, during which their renal, liver, electrolyte, and hepatic statuses remained stable [128]

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In conclusion, ferroptosis is present in MCT-induced PH rats and is involved in the progression of PH