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AstraZeneca conducted fragment-based screening targeting the NAD binding pocket of PHGDH, followed by combinatorial chemical synthesis to generate a large library of compounds

W literaturze opisywany jest przede wszystkim jako stymulator syntezy skadnikw macierzy (kolagen, elastyna, glikozaminoglikany), modulator metaloproteinaz MMP/TIMP, zwizek proangiogenny i nonik miedzi dla enzymw antyoksydacyjnych

People suffering from depression often have low B12 levels

[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Hwang J., Kiick K.L., Sullivan M.O

Importantly, TA1 is not approved by the FDA for autoimmune treatment, so patients should seek medical supervision and consider legal implications