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They were randomized into two groups: L-carnitine group who received L-carnitine 50 mg\kg\day once daily for 1 month before cardiac surgery and control group who received placebo for 1 month before cardiac surgery

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(2023) demonstrated that LPS treatment markedly upregulated the mRNA expression of p38 MAPK in the ileum of mice

The discontinuation of NSAIDs is generally recommended at least a week before surgery to allow platelet function to return to normal

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