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In Quebec, where one in four adults is obese, the current cost of these new drugs (approximately $500 per month) would involve an annual expenditure of several hundred million dollars (in the United States the situation is even worse: the cost of a 72-week course of tirzepatide (15 mg/week) is approximately US$17,000, while the 68-week treatment with semaglutide (2.4 mg/week) is nearly US$23,000!)

For example, the water becomes cloudy, there is something floating in it, or the color changes

This is because metformin reduces the absorption of vitamin B12

Lu H, et al

In some medical studies, inositol has been found to accelerate weight loss and reduce fat (Donne et al., 2019)