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For the scenario of "Understanding Sleep Mechanisms," research data suggests Cortistatin may be more relevant

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And the side effects of remaining B12 deficient are potentially far worse (at best, living a half life - on a good day)

J Med Virol 95:e28158 Keppler-Hafkemeyer A, Greil C, Wratil PR, Shoumariyeh K, Stern M, Hafkemeyer A, Ashok D, Hollaus A, Lupoli G, Priller A (2023) Potent high-avidity neutralizing antibodies and T cell responses after COVID-19 vaccination in individuals with B cell lymphoma and multiple myeloma

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